Now customize the name of a clipboard to store your clips. A considerable amount of literature has accumulated since that time, in which the authors dealing with different classes of Vertebrata, and even those who have studied the question in the same animals, have arrived at widely differing conclusions. Some have believed the spleen to be derived from the mesenchyme of the dorsal mesentery, with or without the participation of the coelomic epithelium; s… In a trauma patient with an injury to the abdomen, the most common symptoms of a ruptured spleen are pain and tenderness of the abdomen, particularly on the left upper quadrant. The splenic artery enters the spleen at the hilus, then that run through the parenchyma or pulp of the spleen. 4-the splenophrenic, which connects the spleen to the diaphragm. • Wedge shaped. As blood enters the abdominal cavity, it can lead to a symptom known as referred pain. Clipping is a handy way to collect important slides you want to go back to later. Similar in structure to a large lymph node, it acts primarily as a blood filter. Dreamy249. 2-the splenorenal, which connects the spleen to the kidney. liver—about 1.4 l (about 3 pt) every minute, Formed at hilum, straight course behind pancreas, Trabecular veinsTrabecular arteriesPulp veinsPenicillar arteriolesFollicle with follicle capillariesArtery with periarterial lymphatic sheath (PALS) 78910Splenic sinusReticular fibrous frameworkOpen capillariesClosed capillaries. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. With the spleen retracted medially, the phrenicocolic ligament is incised. Contractility of the stress fibres allows the formation of slits between the endothelial cells, thereby regulating the passage of blood and blood cells from the red-pulp cords into the sinuses and back into the venous system. Blood from the cords collects in the sinuses (shown by arrows). It functions in a manner. The capsule is deeply indented at the medial aspect of the organ and this indentation is known as hilus (hilum) of the spleen. The spleen is soft, highly vascular and dark purple in colour. See our Privacy Policy and User Agreement for details. The spleen is in the portal circulation. You can change your ad preferences anytime. The question of the origin and early development of the spleenhas been the object of researches since the year 1867. Find PowerPoint Presentations and Slides using the power of XPowerPoint.com, find free presentations research about Function And Structure Of Spleen PPT • Lymphatic organ connected to blood vascular system The reason for this is unknown but may relate to the fact that lower blood pressure allows less rapid flow and minimizes damage to normal erythrocytes. Structure and function of spleen- anatomy, physiology. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. 2- Stores the breakdown products of RBCs site of erythrocyte production in the fetus. Fractures Aida1983. The spleen is encased in a thick connective-tissue capsule. The spleen is a large, encapsulated, bean-shaped organ that is situated on the left side of the body below the diaphragm. 1 At presentation, the spleen is involved in up to 40% of patients with Hodgkin’s disease (HD) and non-Hodgkin’s lymphoma (NHL), and this increases to 70% at postmortem.1, 2, 3 Accurate assessment of the spleen in lymphoma is important because it can alter tumor staging, influence … This is pain that the patient feels somewhere other than where the injury is located. The spleen is divided by function and structure into the red pulp (RP) and white pulp (WP); in between these two regions is the marginal zone (MZ) in rodents and the perifollicular zone in humans (1, 2). Spleen • situated principally in the left hypochondriac region, but its superior extremity extends into the epigastric region 3. No public clipboards found for this slide. 3-the splenocolic, which connects the spleen to the colic flexure and to the thoracic diaphragm. The spleen contains T and B lymphocytes as well as many phagocytes and is a major component of the mononuclear phagocyte system. Spleen Definition. Obliquely along 10 rib, directed downwards, forwards and lat. You can change your ad preferences anytime. Because the red-pulp cords contain a large number of macrophages, ageing erythrocytes that are no longer able to pass through the slits are phagocytosed. If you continue browsing the site, you agree to the use of cookies on this website. Germinal centre Bcells are surface IgD2, while mantle zone B cells coexpress IgM and IgD. Functions of the spleen . Spleen Aida1983. Looks like you’ve clipped this slide to already. The long axis lies along the shaft of the 10th rib, and extends forward only as far as the midaxillary line and cannot be palpated on clinical examination. of areolar plane. … Learn about its function, location in the body, and conditions that can affect the spleen. This function, in combination with a highly organized lymphoid compartment, makes the spleen the most important organ for antibacterial and antifungal immune reactivity. If you continue browsing the site, you agree to the use of cookies on this website. The spleen is surrounded by a capsule of dense connective tissue from which emerge trabeculae, which divide the parenchyma, or splenic pulp, into incomplete compartments.Large trabeculae originate at the hilum, on the medial surface of the spleen; these trabeculae carry nerves, arteries and veins. Blood Circulation in Spleen 3. If you continue browsing the site, you agree to the use of cookies on this website. End of 1 part of doudenum , begins of 2nd part of doudenum Neck - Form the cystic duct, 4cm Hartmann’s Pouch 1. Spleen • Lymphatic organ connected to blood vascular system • Part of mononuclear phagocyte system. An enlarged spleen can be detected by physician examination or via diagnostic imaging. The spleen is an organ found in virtually all vertebrates.Similar in structure to a large lymph node, it acts primarily as a blood filter.The word spleen comes from Ancient Greek σπλήν (splḗn).. Procedures Aida1983. In humans, up to a cup (236.5 ml) of red blood cells can be held in the spleen and released in cases of hypovolemia.
WHERE IS THE SPLEEN LOCATED
... Thymus gland ppt. The venous sinuses consist of a lining of endothelial cells that are positioned in parallel and connected by stress fibres to annular fibres, which are composed of extracellular-matrix components. Clipping is a handy way to collect important slides you want to go back to later. The peritoneum is closely adherent to the outside of the capsule. The spleen can become enlarged as a result of infection, anemia or cancer. • Part of mononuclear phagocyte system. Spleen Clinicas Quirurgicas. All the efferents pass into the intestinal lymph trunks, which then enter the cisterna chyli or the abdominal confluence of lymph trunks. 9 Structure of the spleen. See our User Agreement and Privacy Policy. A component of the lymphatic system, bone marrow functions primarily to produce blood cells and to store fat.Bone marrow is highly vascular, meaning that it is richly supplied with a large number of blood vessels.There are two categories of bone marrow tissue: red marrow and yellow marrow. The spleen. Since the spleen is so rich with blood flow, bleeding from a rupture can be signi… Spleen It lies just beneath the left half of the diaphragm close to the 9th, 10th, and 11th ribs. The red blood cells can be released when needed. The spleen is an organ shaped like a shoe that lies relative to the 9th and 11th ribs and is located in the left hypochondrium and partly in the epigastrium. Lymphoma is the most common malignancy affecting the spleen and may be primary or secondary. Pott's disease- tuberculosis of the spine, An approach to a child with hepatosplenomegaly and lymphadenopathy, Customer Code: Creating a Company Customers Love, No public clipboards found for this slide. The spleen is the largest secondary immune organ in the body and is responsible for initiating immune reactions to blood-borne antigens and for filtering the blood of foreign material and old or damaged red blood cells. Last Updated on January 11, 2020 by Sagar Aryal. C.E. Up to a quarter of lymphocytes can be stored in the spleen at any one time, 1. Bone marrow is the soft, flexible connective tissue within bone cavities. If you continue browsing the site, you agree to the use of cookies on this website. See our Privacy Policy and User Agreement for details. The spleen reaches peak development at puberty, in rats, followed by gradual involution (Losco, 1992). Thus, the spleen is situated between the fundus of the stomach and the diaphragm. The spleen is the largest single mass of lymphatic tissue in the body. It can store platelets in case of an emergency. It also influences antibody formation. The WP is the primary immunologic region of the spleen in both species; however, the WP makes up less than a quarter of splenic tissue. View and Download PowerPoint Presentations on Function And Structure Of Spleen PPT. Structure of GB Fundus -Ant:ant.abdominal wall - Post.inf: transverscolon Body sup: liver stpost.inf: Tr.colon. Presentation Summary : The Spleen Anatomy of Spleen White Pulp Spleen Structure The white pulp is circular in structure and is made up mainly of lymphocytes. Schema of a venous sinus located in the cords of the red pulp. Now customize the name of a clipboard to store your clips. The lymphatic system is the system of ducts and lymph nodes which are found under the skin. The structure of the spleen enables it to remove older erythrocytes from the circulation and leads to the efficient removal of blood-borne microorganisms and cellular debris. Structure and function of Spleen 1. In the adult, the spleen functions mainly as a blood filter, removing old red blood cells. Normal Structure, Function, and Histology of the Spleen MARK F. C ESTA Integrated Laboratory Systems, Inc., Durham, North Carolina 27713, USA ABSTRACT The spleen is the largest secondary immune organ in the body and is responsible for initiating … Figure 19. WebMD's Spleen Anatomy Page provides a detailed picture, definition, and information about the spleen. The stress fibres run along the long axis of the endothelial cells and are most prominent where the endothelial cells are in contact. Thymus & Spleen Sarah Murray sgm2106@columbia.edu November 30, 2005 Are you getting immune to exam blocks yet?? Spleen is located in left upper part of abdomen or hypochondrium. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. The mesenchymal cells differentiate into the parenchymal cells, connective tissue and the surface capsule. 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